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Sulfonamide: major side effects

· Sulfonamide side effects:
Steven-Johnson syndrome
Skin rash
Solubility low (causes crystalluria)
Serum albumin displaced (causes newborn kernicterus and potentiation of other serum albumin-binders like warfarin)
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---Robert O'Connor University College Dublin

Complement cascade initiating items: alternative vs. classic

Classic: Combined Complexes.
Alternative: Activators Alone, or IgA.
· Complexes are made of Ab and Ag combined together.
· Examples of activators: endotoxin, microbial surface.
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---Robert O'Connor University College Dublin

Sjogren syndrome: morphology

"Jog through the MAPLES":
· Sjogren is:
Mouth dry
Arthritis
Parotid enlarged
Lymphoma
Eyes dry
Sicca (primary) or Secondary
· See diagram.

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---Robert O'Connor University College Dublin

Hypersensitivity: type IV example

Poison IVy causes type IV hypersensitivity.
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---Anonymous Contributor

Interferon gamma: action on macrophages

"Th1nk BIG Mac Attack":
Th1 and NK cells Build Interferon Gamma.
Causes Macrophages to have an augmented Attack [by better lysosome function and increasing reactive oxygen metabolites, nitric oxide and defensins].
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---Lior Greenberg Technion Faculty of Medicine, Haifa, Israel

Passive vs. active immunity

"Pay for Passive, Active Ages":
Passive:Pay for a shot of antibodies for fast results following exposure to Rabies, etc.
Active: Slow onset ("aging") and memory.
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---Lior Greenberg Technion Faculty of Medicine, Haifa, Israel

DiGeorge/ Velocardiofacial syndrome: features

CATCH 22:
Cardiac abnormalities
Abnormal facies
Thymic aplasia
Cleft palate
Hypocalcemia
22q11 deletion
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---Anonymous Contributor

Polycythemia Rubra Vera (PRV): common symptoms

PRV:
Plethora/ Pruritis
Ringing in ears
Visual blurriness
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---Rinku S. Uberoi UNIBE

HIV infection: high-risk groups

HIV:
Homosexuals/ Hemophiliacs
IV drug abusers
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---Anonymous Contributor

Basophil vs. eosinophils: effect for allergic persons

Basophils are "Bad-o-phils" because they contribute to our allergic reactions.
Eosinophils are "Easy-on-me-phils" because they counteract our allergic reactions.
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---Andrew Hammer