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Alzheimer's disease: common characteristics

ALZHEIMER'S:
Anterograde amnesia is usually first sign
Life expectancy increase shows more cases in recent years
Zapped (loss of) acetylcholinergic neurons
Hereditary disease
Entire hippocampus becomes affected
Identified by neurofibrillary tangles
Mutation in amyloid genes associated w/ disease
Entorhinal areas degenerate first
Retrograde amnesia ultimaltely develops
Senile plaques are formed at synapse
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---David H. Chafey Ponce School of Medicine

Thalamic boundaries

"I HIT PPL (people)":
· Directions are in alphabetical order:
Anterior: Interventricular Foramen
Inferior: Hypothalamic nuclei (plane connecting them)
Lateral: Internal capsule (posterior limb)
Medial: Third ventricle
Posterior: free Pole of Pulvinar
Superior: Lateral ventricle
· Posterior has 2 P's.
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---David Colbert University of Western Australia

Dysphasia: Broca's vs. Wernicke's causing expressive vs. receptive

BEWARE:
Broca's area: Expressive dysphasia.
Wernicke's Area: REceptive dysphasia.
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---Tosan Okoro LWMS

Meningitis: site of TB meningitis attack

TB meningitis attacks The Base of the brain
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---Marc Serret Medical College of Wisconsin